Lacking a formal narrative, Warhol's mammoth film follows various residents of the Chelsea Hotel in 1966 New York City. The film was intended to be screened via dual projector set-up.

The film depicts a rehearsal of The Velvet Underground including Nico, and is essentially one long loose improvisation.

Five lonesome cowboys get all hot and bothered at home on the range after confronting Ramona Alvarez and her nurse.

Andy Warhol directs a single 35-minute shot of a man's face to capture his facial expressions as he receives the sexual act depicted in the title.

Set on Fire Island, My Hustler depicts competition over the affections of a young male hustler among a straight woman, a former male hustler, and the man who hired the boy's companionship via a "Dial-A-Hustler" service.