Conducting clandestine experiments within the morgue at Miskatonic University, scientist Herbert West reveals to a fellow graduate student his groundbreaking work concerning the re-animation of fresh corpses.

During World War II, Steve Rogers is a sickly man from Brooklyn who's transformed into super-soldier Captain America to aid in the war effort. Rogers must stop the Red Skull – Adolf Hitler's ruthless head of weaponry, and the leader of an organization that intends to use a mysterious device of untold powers for world domination.

Mild-mannered Clark Kent works as a reporter at the Daily Planet alongside his crush, Lois Lane. Clark must summon his superhero alter-ego when the nefarious Lex Luthor launches a plan to take over the world.

Bruce Banner, a genetics researcher with a tragic past, suffers massive radiation exposure in his laboratory that causes him to transform into a raging green monster when he gets angry.

A teenage Peter Parker grapples with both high school and amazing super-human crises as his alter-ego Spider-Man.