Rie Kuwana (桑名 里瑛, Kuwana Rie, born October 2, 1993, in Ibaraki Prefecture) is a Japanese actress and former child actress. Throughout her career, she has worked in television, film, theatre, radio, and commercial advertising, appearing in a variety of drama series, films, and stage productions.

A graduate of Jōsō Gakuin High School, Kuwana was represented by Akiyama Office until May 2022. She is best known for playing Marie, the cheeky young girl who confronts Ritsuko Tanaka in television commercials for Tsumura's Sofure product line.