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Isabel Sanford (born Eloise Gwendolyn Sanford; August 29, 1917 – July 9, 2004) was an American stage, film, and television actress and comedian best known for her role as Louise "Weezy" Mills Jefferson on the CBS sitcoms All in the Family (1971–1975) and The Jeffersons (1975–1985). In 1981, she became the second African-American actress to win a... more