Affonso Uchôa was born in the city of Contagem, in Brazil. He studied cinema in Minas Gerais and began his career as an assistant director. He debuted as a director in A Vizinhança do Tigre (2016), a docudrama awarded at the Mostra de Cinema de Tiradentes. His next feature Arábia (2017) won the main awards at Festival de Brasília. He also directed the short-film Sete Anos em Maio (2019).