In post-9/11 New York City, an eclectic group of citizens find their lives entangled, personally, romantically, and sexually, at Shortbus, an underground Brooklyn salon infamous for its blend of art, music, politics, and carnality.

Singapore Sling pursues Laura, a romantic memory from his past. One night, he finds himself at a mysterious villa, watching two women bury a body. He falls into their trap and, in an atmosphere of isolation and decadence, the trio act out insane pleasure games and a ritual of blood and murder.

Almost a decade since larger-than-life glam-rock enigma Brian Slade disappeared from public eye, an investigative journalist is on assignment to uncover the truth behind his former idol.

In Los Angeles, a colorful assortment of bohemians try to make sense of their intersecting lives. The moody Dark Smith, his bisexual girlfriend, her lesbian lover and their shy gay friend plan on attending the wildest party of the year. But they'll only make it if they can survive the drug trips, suicides, trysts, mutilations and alien...

Gabriel is a young, aspiring musical composer whose life seems stuck in the First Act. When his new musical number gets a critical reception, a theatre colleague, Perry, tells Gabriel that he needs to get a life before he can write about one – so he heads straight for his local gay bar.