Some of Sin City's most hard-boiled citizens cross paths with a few of its more reviled inhabitants.

Laura and John, grieved by a terrible loss, meet in Venice, where John is in charge of the restoration of a church, two mysterious sisters, one of whom gives them a message sent from the afterlife.

A group of New Yorkers caught up in their romantic/sexual milieu converge at Shortbus, an underground Brooklyn salon infamous for its blend of art, music, politics, and carnality, and loosely inspired by various underground NYC gatherings that took place in the early 2000s. Here, gay couple Jamie (PJ DeBoy) and James (Paul Dawson) meet...

When Scott learns that his longtime cyber-buddy from Berlin is a gorgeous young woman, he and his friends embark on a trip across Europe.

As sadomasochistic yakuza enforcer Kakihara searches for his missing boss he comes across Ichi, a repressed and psychotic killer who may be able to inflict levels of pain that Kakihara has only dreamed of.