A troubled Southern man talks to his suicidal sister's psychiatrist about their family history and falls in love with her (and New York City) in the process.

Three sisters - Georgia, Eve, and Maddy - do what they do best with life, love, and lunacy on the telephone lines that bind - when their curmudgeonly father, Lou, is admitted to a Los Angeles Hospital. After years of wild living, intermittent affection, and constant phoning, he is finally threatening to die.

Fanny Price is sent to live with her wealthy relatives, the Bertrams, where she is treated poorly by most except her cousin Edmund. Her life is complicated by the arrival of the worldly Mary and Henry Crawford.

Ruža left Serbia, her country, over 30 years ago and lives in Zurich. Her daily life is a string of repetitive moments until, one day, Ana arrives on the scene and upsets Ruža's painstakingly organized world. A subtle friendship develops between the two strong willed women.

After getting into a car accident while drunk on the day of her sister's wedding, Gwen Cummings is given a choice between prison or a rehab center. She chooses rehab, but is extremely resistant to taking part in any of the treatment programs they have to offer, refusing to admit that she has an alcohol addiction.