The seemingly invincible Spider-Man goes up against an all-new crop of villains—including the shape-shifting Sandman. While Spider-Man’s superpowers are altered by an alien organism, his alter ego, Peter Parker, deals with nemesis Eddie Brock and also gets caught up in a love triangle.

After being held captive in an Afghan cave, billionaire engineer Tony Stark creates a unique weaponized suit of armor to fight evil.

During World War II, Steve Rogers is a sickly man from Brooklyn who's transformed into super-soldier Captain America to aid in the war effort. Rogers must stop the Red Skull – Adolf Hitler's ruthless head of weaponry, and the leader of an organization that intends to use a mysterious device of untold powers for world domination.

Bruce Banner, a genetics researcher with a tragic past, suffers massive radiation exposure in his laboratory that causes him to transform into a raging green monster when he gets angry.

The Fantastic Four return to the big screen as a new and all powerful enemy threatens the Earth. The seemingly unstoppable 'Silver Surfer', but all is not what it seems and there are old and new enemies that pose a greater threat than the intrepid superheroes realize.