Pleasantly plump teenager Tracy Turnblad auditions to be on Baltimore's most popular dance show - The Corny Collins Show - and lands a prime spot. Through her newfound fame, she becomes determined to help her friends and end the racial segregation that has been a staple of the show.

While conducting a research experiment intended to bring about an alternative to modern surgery, exhausted Los Angeles surgeon Dr. Daniel Jekyll falls asleep and accidentally inhales the white powders, transforming him into a wildly uninhibited nymphomaniac.

Broadway director Julian Marsh needs just one more hit show so he can retire and recover his health. It looks like he just may pull it off until temperamental star Dorthy Brock breaks her ankle on the eve of the show's premiere and has to be replaced by her understudy Peggy.

Rufus T. Firefly is named president/dictator of bankrupt Freedonia and declares war on neighboring Sylvania over the love of wealthy Mrs. Teasdale.

Showman Jerry Travers is working for producer Horace Hardwick in London. Jerry demonstrates his new dance steps late one night in Horace's hotel room, much to the annoyance of sleeping Dale Tremont below. She goes upstairs to complain and the two are immediately attracted to each other. Complications arise when Dale mistakes Jerry for ...