Two teenage couples traveling across the backwoods of Texas searching for urban legends of serial killers end up as prisoners of a bizarre and sadistic backwater family of serial killers.

In October of 1994 three student filmmakers disappeared in the woods near Burkittsville, Maryland, while shooting a documentary. A year later their footage was found.

A mysterious video has been linked to a number of deaths, and when an inquisitive journalist finds the tape and views it herself, she sets in motion a chain of events that puts her own life in danger.

It is a variation on the original legend of Alraune in which a Mad Scientist creates a beautiful but demonic child from the forced union between a woman and a Mandrake root. Not to be confused with the 1918 German version of Alraune.

A world-famous pianist loses both hands in an accident. When new hands are grafted on, he is horrified to learn they once belonged to a murderer.