An introverted man receives an anonymous letter from an ex-lover informing him that he has a son who may be looking for him. A freelance sleuth neighbor motivates the man to embark on a cross-country search for his past flames, seeking answers.

It is 1967, and Larry Gopnik, a physics professor at a quiet Midwestern university, has just been informed by his wife Judith that she is leaving him. He scrambles to find a semblance of meaning as he loses control of nearly every aspect of his life.

Paris-based wine expert Steven Spurrier heads to California in search of cheap wine that he can use for a blind taste test in the French capital. Stumbling upon the Napa Valley, the stuck-up Englishman is shocked to discover a winery turning out top-notch chardonnay. Determined to make a name for himself, he sets about getting the booz...

Two women, Nic and Jules, brought a son and daughter into the world through artificial insemination. When one of their children reaches age, both kids go behind their mothers' backs to meet with the donor. Life becomes so much more interesting when the father, two mothers and children start to become attached to each other.

When down-on-his-luck part-time high school wrestling coach Mike agrees to become legal guardian to an elderly man, his ward's troubled grandson turns out to be a star grappler, sparking dreams of a big win -- until the boy's mother retrieves him.