A wheelchair-bound photographer spies on his neighbors from his apartment window and becomes convinced one of them has committed murder.

Novelist Paul Sheldon crashes his car on a snowy Colorado road. He is found by Annie Wilkes, the "number one fan" of Paul's heroine Misery Chastaine. Annie is also dangerously unstable, and Paul finds himself crippled, drugged, and at her mercy.

A man who specializes in debunking paranormal occurrences checks into the fabled room 1408 in the Dolphin Hotel. Soon after settling in, he confronts genuine terror.

Walter Sparrow is an animal control officer that becomes obsessed with a mysterious book that seems to be based on his own life. As soon as he opens the book, he notices strange parallels between what he reads and what he's experienced. But now he's worried that a fictional murder might materialize.

David Callaway tries to piece together his life in the wake of his wife's suicide and has been left to raise his nine-year-old daughter, Emily on his own. David is at first amused to discover that Emily has created an imaginary friend named 'Charlie', but it isn't long before 'Charlie' develops a sinister and violent side, and as David...