At the American Computer Chess Convention, enthusiasts gather to pit their programs against other computer chess programs and human players in a tournament for a grand prize of $7500.

Unsure of what to do next, 23-year-old Marnie tries her best to navigate life after college. Still partying like there's no tomorrow, Marnie drags herself out of bed for her miserable temp job and can't decide whether she's wasting her time going after best buddy Alex, who doesn't seem to be interested.

Alan is a musician who leaves a busted-up band for New York, and a new musical voyage. He tries to stay focused and fends off all manner of distractions, including the attraction to his good friend's girlfriend.

Jeannie and her estranged business partner Amanda have a falling out leading to Amanda getting back with an ex and Jeannie bonding more with her non-paralyzed twin Lauren.

Walter Francis and Jerry Peoples, two characters from "Mutual Appreciation", share a visit at the Peoples' home in the countryside.