Two years have passed since the final battle with Sephiroth. Though Midgar, city of mako, city of prosperity, has been reduced to ruins, its people slowly but steadily walk the road to reconstruction. However, a mysterious illness called Geostigma torments them. With no cure in sight, it brings death to the afflicted, one after another...

Led by a strange dream, scientist Aki Ross struggles to collect the eight spirits in the hope of creating a force powerful enough to protect the planet. With the aid of the Deep Eyes Squadron and her mentor, Dr. Sid, Aki must save the Earth from its darkest hate and unleash the spirits within.

Determined to prove its superiority, a bio-engineered Pokémon called Mewtwo lures Ash, Pikachu and others into a Pokemon match like none before.

When Me Snowdon's sadness of her father's disappearance get to her, she unknowingly uses the Unknown to create her own dream world along with Entei, who she believes to be her father. When Entei kidnaps Satoshi's mother, Satoshi along with Kasumi & Takeshi invade the mansion looking for his mom and trying to stop the mysteries of Me's ...

Satoshi must put his skill to the test when he attempts to save the world from destruction. The Greedy Pokemon collector Gelardan throws the universe into chaos after disrupting the balance of nature by capturing one of the Pokemon birds that rule the elements of fire, lightning and ice. Will Satoshi have what it takes to save the world?