After being bitten by a genetically altered spider at Oscorp, nerdy but endearing high school student Peter Parker is endowed with amazing powers to become the superhero known as Spider-Man.

The seemingly invincible Spider-Man goes up against an all-new crop of villains—including the shape-shifting Sandman. While Spider-Man’s superpowers are altered by an alien organism, his alter ego, Peter Parker, deals with nemesis Eddie Brock and also gets caught up in a love triangle.

Scientist Bruce Banner scours the planet for an antidote to the unbridled force of rage within him: the Hulk. But when the military masterminds who dream of exploiting his powers force him back to civilization, he finds himself coming face to face with a new, deadly foe.

After being held captive in an Afghan cave, billionaire engineer Tony Stark creates a unique weaponized suit of armor to fight evil.

During World War II, Steve Rogers is a sickly man from Brooklyn who's transformed into super-soldier Captain America to aid in the war effort. Rogers must stop the Red Skull – Adolf Hitler's ruthless head of weaponry, and the leader of an organization that intends to use a mysterious device of untold powers for world domination.