The hopes and dreams of four ambitious people are shattered when their drug addictions begin spiraling out of control. A look into addiction and how it overcomes the mind and body.

Years after their teenage daughter’s death, Lois and Doug Riley, an upstanding Indiana couple, are frozen by estranging grief. Doug escapes to New Orleans on a business trip. Compelled by urgencies he doesn’t understand, he insinuates himself into the life of an underage hooker, becoming her platonic guardian.