A man with a low IQ has accomplished great things in his life and been present during significant historic events—in each case, far exceeding what anyone imagined he could do. But despite all he has achieved, his one true love eludes him.

Lester Burnham, a depressed suburban father in a mid-life crisis, decides to turn his hectic life around after developing an infatuation with his daughter's attractive friend.

Selma, a Czech immigrant on the verge of blindness, struggles to make ends meet for herself and her young son, who has inherited the same genetic disorder and will suffer the same fate without an expensive operation. When life becomes increasingly difficult, Selma learns to cope through her love of musicals, dreaming up little numbers ...

Romain, 31, a fashion photographer with terminal cancer, elects to die alone, preparing others to live past him rather than prolong the inevitable with chemotherapy or be smothered in sympathy by those who know him.

A small town teenager in the 1960s believes her dreams of becoming a famous singer will come true when her rock star idol gets stranded in town. But a leak in a nearby chemical plant that is believed to be causing mass mutations threatens to turn her dream into a nightmare.