Some of Sin City's most hard-boiled citizens cross paths with a few of its more reviled inhabitants.

An ex-tennis pro carries out a plot to have his wife murdered after discovering she is having an affair, and assumes she will soon leave him for the other man anyway. When things go wrong, he improvises a new plan—to frame her for murder instead.

As they celebrate their high school graduation, four friends are involved in a hit-and-run accident when their car hits and apparently kills a pedestrian on an isolated roadway. They dispose of the body and vow to keep the incident a secret, a year later somebody starts sending them letters bearing the warning "I Know What You Did Last...

A man obsessed with conspiracy theories becomes a target after one of his theories turns out to be true. Unfortunately, in order to save himself, he has to figure out which theory it is.

Tells the seemingly random yet vitally connected story of a set of incidents that all converge one evening at 11:14pm. The story follows the chain of events of five different characters and five different storylines that all converge to tell the story of murder and deceit.